• Alcohol and drug use are leading causes of illness and death in the U.S., yet substance use disorders (SUDs) are greatly under-recognized in medical settings.
• Many studies have examined barriers to implementing screening for substance use in primary care, however, most of the…

• N-acetylcysteine (NAC) is an over-the-counter antioxidant with potential promise as a treatment option for substance use disorders.
• Little research has been done on NAC as a treatment for alcohol use disorder (AUD), however.
• This secondary analysis of data from the NIDA…

• The majority of health care resources in the U.S. are utilized by a small population characterized as high-risk, high-need persons with complex care needs (e.g., adults with multiple chronic conditions).
• Substance use disorders (SUDs) and mental health disorders (MHDs) are a…

• Tobacco use is a major health risk for people with substance use disorders (SUDs).
• Clients in SUD treatment smoke at 3-4 times the rate of the general population, tend to smoke more heavily, and are less likely to quit successfully.
• In addition to persons in SUD…

• There are higher rates of menthol cigarette smoking within certain population subgroups.
• Limited research has examined menthol use among individuals in treatment for substance use disorders (SUD), a population with a high prevalence of cigarette smoking, poor smoking cessation…

• The NIDA Clinical Trials Network study, Stimulant use Reduction Intervention using Dosed Exercise (STRIDE) (CTN-0037), was a randomized controlled trial comparing a 12 kcal/kg/week (KWW) exercise dose versus a health education control for the treatment of stimulant use disorder.

• In order to advance understanding of the causes and effects of cannabis use, define excessive or problematic use, and develop effective interventions for those who need help quitting or cutting back, researchers first need a reliable system for measuring quantity and frequency of use.…

• People living with HIV (PLWH) who use substances continue to have shorter life expectancies and worse health outcomes than PLWH who do not use substances.
• Another important contributor to factors that can affect the health of PLWH who use substances is these individuals’ frequent…

• A growing body of evidence suggests that chronic substance users have higher rates of cognitive impairment than the general population.

Impairment also seems to differ by type of substance use disorder (SUD), with different types of impairment (…

• Motivational interviewing (MI) is an evidence-based practice shown to be effective when working with people in treatment for substance use disorders.

However, MI comprises a complex set of skills that are not easy to master, so training requires valid measurement of fidelity…