The U.S. has been experiencing a devastating opioid epidemic with enormous negative impacts on public health across the country. While efforts to reduce opioid prescribing have been successful, rates of opioid use disorder (OUD) continue to surge, with 300-400% increases among some populations.…
CTN Research Briefs for ASME: People with Opioid Use Disorder Less Likely to Be Engaged/Retained in Treatment for HIV
Despite significant advances in HIV treatment, marginalized groups continue to be disproportionately impacted by the virus. People who use drugs remain one of the most challenging groups to engage and retain in HIV care and are also more likely to engage in behaviors that increase…
CTN Briefs for Addiction Science Made Easy: Pain, Depression, and Relapse in Patients Receiving Buprenorphine/Naloxone Treatment for Opioid Use Disorder
Pain and depression often co-occur during treatment for opioid use disorder, but not much is known about how they influence relapse for patients with a primary diagnosis of prescription opioid use disorder (POUD).
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CTN Briefs for Addiction Science Made Easy: How Does Pain Intersect with Medication Treatment for Opioid Use Disorder?
Comorbid pain and opioid use disorder (OUD) are common, with about 1 in 3 individuals on chronic opioid therapy for pain also meeting criteria for OUD. Despite this high percentage, however, few studies of people with OUD have considered pain as a moderator of treatment success.
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Patients with Co-Occurring SUD and Chronic Conditions Seen More Often by Primary Care Providers, Receive More Opioid Prescriptions
Patients with a substance use disorder (SUD) often present with co-occurring chronic conditions in primary care. Despite this fact, little is known about whether chronic condition outcomes or related service utilization in primary care varies between patients with or without SUD.…
MOMs Study in CTN to Evaluate Buprenorphine (Sustained Release vs. Extended Release) in Pregnant Women
The opioid epidemic in the United States has been associated with a corresponding increase in the number of pregnant women with opioid use disorder (OUD) and infants diagnosed with neonatal opioid withdrawal syndrome (NOWS) resulting from exposure to opioids in utero.…
Clinical Decision Support for Opioid Use Disorders: NIDA CCTN Working Group Report
There is an urgent need for strategies to address the U.S. epidemic of prescription opioid, heroin, and fentanyl-related overdoses, misuse, addiction, and diversion. Evidence-based treatments like medications for opioid use disorder (MOUD) are available, but…
Predictors of HIV Sex Risk Behavior Among Women in Treatment for Substance Use Disorders
In the U.S., women account for about 1 in 5 new HIV infections annually, with the vast majority of these (84%) from heterosexual contact. Substance use is often a driver of HIV transmission, either through a partner who is HIV+ and uses drugs or via sexual…
Patient Navigators Find Contingency Management to be Helpful for Patients with HIV and SUD
Patient navigation is a patient-centered approach to care coordination that helps people overcome barriers to receiving and adhering to health care. Patient navigation has been effective in linking people to HIV care, but some people who have both untreated…