Comorbid pain and opioid use disorder (OUD) are common, with about 1 in 3 individuals on chronic opioid therapy for pain also meeting criteria for OUD. Despite this high percentage, however, few studies of people with OUD have considered pain as a moderator of treatment success.

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Patients with a substance use disorder (SUD) often present with co-occurring chronic conditions in primary care. Despite this fact, little is known about whether chronic condition outcomes or related service utilization in primary care varies between patients with or without SUD.…

The opioid epidemic in the United States has been associated with a corresponding increase in the number of pregnant women with opioid use disorder (OUD) and infants diagnosed with neonatal opioid withdrawal syndrome (NOWS) resulting from exposure to opioids in utero.…

There is an urgent need for strategies to address the U.S. epidemic of prescription opioid, heroin, and fentanyl-related overdoses, misuse, addiction, and diversion. Evidence-based treatments like medications for opioid use disorder (MOUD) are available, but…

In the U.S., women account for about 1 in 5 new HIV infections annually, with the vast majority of these (84%) from heterosexual contact. Substance use is often a driver of HIV transmission, either through a partner who is HIV+ and uses drugs or via sexual…

Patient navigation is a patient-centered approach to care coordination that helps people overcome barriers to receiving and adhering to health care. Patient navigation has been effective in linking people to HIV care, but some people who have both untreated…

Despite the existence of safe and effective FDA-approved medications for opioid use disorder (OUD), only a small percentage of individuals with OUD receive treatment and the rate of returning to opioid use after treatment is relatively high.…

Evidence-based treatment of opioid use disorder (OUD) includes medication treatment with methadone, buprenorphine, or naltrexone. However, the large number of people needing treatment for OUD currently outstrips treatment capacity, and improving access to OUD…

Approximately 12% of people who have used cannabis in the past year are estimated to have cannabis use disorder (CUD). Forty percent of people with a diagnosis of CUD also meet criteria for a mood disorder, with major depressive disorder (MDD) being the…

Substance use disorders (SUD) are common in individuals with HIV, and untreated SUD is associated with increased HIV risk behaviors, decreased use of and/or adherence to antiretroviral therapy, decreased viral suppression, and greater HIV-related symptoms.…