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May 1, 2000

The Power of the Mother-Child Bond

  • An infant is extraordinarily sensitive to its mother’s behavior
  • Baby rats nursed by their intoxicated mothers exhibit greater overall distress and aversion to alcohol
  • The infants’ distress and aversion seem dependent on maternal reaction to alcohol
  • Alcohol’s…
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May 1, 2000

Mighty Things From Small Beginnings

  • Tiny fragments of cells called platelets are responsible for clotting
  • Clotting after injury stops bleeding; clotting within a blood vessel can obstruct blood flow to the heart muscle, leading to a heart attack
  • Alcohol may ‘thin’ the blood, thereby reducing the chances of…
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May 1, 2000

Biomarkers: Testing for Alcohol Consumption Among Women

  • Heavy alcohol consumption can cause biochemical changes in the body
  • Testing for specific biochemical markers is one way of establishing the likelihood of problem drinking
  • Biochemical markers tend to be less sensitive for women than for men

In addition to…

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May 1, 2000

African-American Alcoholics: At Greater Risk for Immune Disorders?

  • Alcoholism is known to compromise the immune system
  • African-American alcoholics are at greater risk for certain infectious diseases
  • African-American ethnicity, in conjunction with alcoholism, seems to signify a more compromised immune system
  • These immune…
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June 1, 2000

Some Alcoholics May Self-Medicate With Carbohydrates Between Drinks

  • Alcoholics have reduced levels of serotonin, a brain chemical
  • Alcohol increases serotonin levels, as do carbohydrates
  • Those alcoholics with high cravings for carbohydrates have a unique response to specific diets
  • Carbohydrate craving may be an important clue in…
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June 1, 2000

“Falling Down Drunk” Is Not a Laughing Matter

  • Excessive alcohol consumption clearly has a deleterious effect on brain structure and function
  • Gait and balance, followed by visuospatial abilities, show the greatest alcohol-related deficits
  • Two principal neural systems, the cerebellar-frontal and the corticocortical…
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June 1, 2000

Parenting, Stress and Your Child’s Risk for Alcoholism

  • A recent study has found that the absence of a parent as role model can be stressful for infants
  • Concentrations of cortisol, a principal stress hormone, can indicate levels of stress
  • Infant monkeys who had high cortisol levels as a stress response later drank heavily as…
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June 1, 2000

Alcohol and Thiamine Deficiency Together: A Dangerous Combination?

  • Heavy alcohol use is associated with thiamine (Vitamin B1) deficiency
  • Alcohol and thiamine deficiency together may have a more damaging impact on the brain
  • Learning and reference memory appear to be the most sensitive to their synergistic effects
  • The role of…
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July 1, 2000

Can Heavy Alcohol Use Lead to Some Kinds of Cancer?

  • A significant proportion of Asians lack the aldehyde dehydrogenase-2 (ALDH2) gene
  • Acetaldehyde is produced in saliva while drinking alcohol
  • ALDH2-deficient individuals who drink heavily appear unable to eliminate salivary acetaldehyde
  • These same individuals…
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July 1, 2000

Using PET Scan Technology to Study Alcohol’s Effects on the Brain

  • Alcohol has both sedative-like and stimulant-like effects on the brain
  • Benzodiazepines, which have a sedative effect, are used as sleeping pills
  • Alcohol and benzodiazepines both facilitate brain GABA activity, which is the main inhibitory neurotransmitter system in the…
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