The South Africa HIV Addiction Technology Transfer Centre (ATTC) was launched on 17-18 January, 2018 in Cape Town, South Africa.  The launch event was attended by representatives from 20 unique organisations.  These included regional and national non-governmental organisations involved in the delivery of care for HIV, substance use disorders and mental illness; as well as provincial and national government. Attendees shared their expertise and provided strategic input to the newly formed ATTC. The launch event additionally marked the constitution of the National Advisory Board, whose ongoing strategic and technical contribution will greatly assist the ATTC in ensuring the appropriateness and relevance of our training and technical assistance offerings.  The new ATTC represents a strategic partnership between the University of Cape Town’s Department of Psychiatry and Mental Health (Division of Addiction Psychiatry) and Brown University School of Public Health, home to one of the longest standing ATTCs, the New England ATTC.