Regional Psychosocial Support Initative (REPSSI) is a non-profit organisation working to lesson the social and psychosocial (emotional) impact of poverty, conflict, HIV and AIDS among children and youth in 13 Eastern and Southern African countries. Attendees will gain knowledge around cultural competencies to better conceptualise the circumstances and care of their patients in order to improve HIV treatment outcomes through strategies such as increased detection and intervention of co-occurring mental, alcohol and other drug use disorders.