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Addiction Science Made Easy (ASME)

Research Brief Catalog

Addiction Science Made Easy, currently written by Meg Brunner, MLIS (Northwest ATTC and the NIDA CTN Dissemination Library), features two research papers per month, explaining the science in clear language and putting the findings in context for addiction workforce members. One paper typically comes from NIDA’s National Drug Abuse Treatment Clinical Trials Network (CTN), the other from a SAMHSA-funded project.
Different Patterns of Polysubstance Use Predict Relapse for People in Treatment for Opioid Use Disorders
Meg Bruner, MLIS
Pan Y, et al. Specific polysubstance use patterns predict relapse among patients entering opioid use disorder treatment. Drug and Alcohol Dependence Reports 2022;5:100128. Find it in the CTN Dissemination Library
Published: January 1, 2023
Single-Item Measure Helps Providers Screen for Cannabis Use Disorder 
Meg Brunner, MLIS
Matson TE, et al. Validity of the Single-Item Screen-Cannabis (SIS-C) for Cannabis Use Disorder Screening in Routine Care. JAMA Network Open 2022 (in press).
Published: January 12, 2022
Hands-On Naloxone Training is Beneficial for Rural Clinicians and Staff 
Meg Brunner, MLIS
Cody SL, et al. An exploratory study of a hands-on naloxone training for rural clinicians and staff. Journal of Nursing Scholarship 2022 (in press). (Need help getting a copy of this article? Contact Meg at [email protected].)
Published: January 12, 2022
Deaf & Hard of Hearing People Lack Access to Communication in Mental Health & Substance Use Treatment Facilities
Meg Brunner, MLIS
Citation: James TG et al. Communication access in mental health and substance use treatment facilities for Deaf American Sign Language users. Health Affairs 2022;41(10):1413-1422.
Published: January 11, 2022
Counseling and/or 12-Step Attendance Improves Outcomes for People on Medications for Opioid Use Disorder
Meg Brunner, MLIS
Hefner K, et al. Time-lagged association between counseling and/or 12-Step attendance with subsequent opioid use in a secondary analysis from a randomized, clinical trial of medications for opioid use disorder. Drug and Alcohol Dependence Reports 2022;5:100100.
Published: January 11, 2022
Social Media Platforms, Dating Apps, or Search Engines – Which Work Best for Promotion of HIV Self-Testing?
Meg Brunner, MLIS
Stafylis C, et al. Relative effectiveness of social media, dating apps, and information search sites in promoting HIV self-testing: Observational cohort study. JMIR Formative Research 2022; 6(9):e35648.
Published: January 10, 2022
What is the Best Dosing Strategy for Buprenorphine or Methadone to Prevent Relapse?
Meg Brunner, MLIS
Rudolph KE, et al. Buprenorphine & methadone dosing strategies to reduce risk of relapse in the treatment of opioid use disorder. Drug and Alcohol Dependence 2022;239:109609. Find it in the CTN Dissemination Library.
Published: January 10, 2022
Residential vs. Outpatient Treatment for OUD: Which One Works Best?
Meg Brunner, MLIS
Hartung DM, et al. Association between treatment setting and outcomes among Oregon Medicaid patients with opioid use disorder: A retrospective cohort study. Addiction Science & Clinical Practice 2022;17:45.
Published: January 9, 2022
What Patient Characteristics Might Predict Successful Treatment Outcomes for Opioid Use Disorder?
Meg Brunner, MLIS
Greiner MG, et al. Patient characteristics associated with opioid abstinence after participation in a trial of buprenorphine versus injectable naltrexone. Substance Use & Misuse 2022;57(11):1732-1742.
Published: January 9, 2022
Depression in Patients Prescribed Opioids for Pain Tied to Increased Rates of Substance Misuse, Overdose, Pain, Poorer Health Outcomes
Meg Brunner, MLIS
Brown JL, et al. Associations between elevated depressive symptoms and substance use, prescription opioid misuse, overdose history, pain, and general health among community pharmacy patients prescribed opioids. Substance Abuse 2022;43(1):1110-1115.
Published: January 8, 2022
Do Medications for Opioid Use Disorder Cause Weight Gain?
Meg Brunner, MLIS
Manza P, et al. Sex differences in weight gain during medication-based treatment for opioid use disorder: A meta-analysis and retrospective analysis of clinical trial data. Drug and Alcohol Dependence 2022;238:109575. Find it in the CTN Dissemination Library.
Published: January 8, 2022
Confidential Survey Reveals Most Patients Who Use Cannabis for Health Reasons Don’t Tell Their Providers
Meg Brunner, MLIS
Lapham GT, et al. Comparison of medical cannabis use reported on a confidential survey vs. documented in the electronic health record among primary care patients. JAMA Network Open 2022;5(5):e2211677. Read this article for free online: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2792539
Published: January 7, 2022
Identifying Counties at Higher Risk for Mortality from COVID-19 and Opioid Overdose
Meg Brunner, MLIS
Zhu Y, et al. Social determinants of mortality of COVID-1 and opioid overdose in American rural and urban counties. Journal of Addiction Medicine 2022;16(1):e52-e55. Read this article for free online:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815643/
Published: January 7, 2022
Opioid Use Disorder Treatment with Buprenorphine or Naltrexone Helps with Co-Occurring Depression and Suicidal Ideation
Meg Brunner, MLIS
Na PJ, et al. Co-occurring depression and suicidal ideation in opioid use disorder: Prevalence and response during treatment with buprenorphine-naloxone and injection naltrexone. J Clin Psychiatry 2022;83(3):21m14140. Find it in the CTN Dissemination Library.
Published: January 6, 2022
Pain Severity and Interference Associated with Increased Use of Substances – But Differently for Women and Men
Meg Brunner, MLIS
Charron E, et al. Pain severity and interference and substance use among community pharmacy patients prescribed opioids: A secondary analysis of the PHARMSCREEN study. J Pain 2022 (in press). Find it in the CTN Dissemination Library.
Published: January 6, 2022
Education and Prior Treatment Attempts Predict Stronger and Earlier Therapeutic Alliance for Black Women with PTSD and SUD, But Not Treatment Outcomes
Meg Brunner, MLIS
Bauer AG, et al. Predictors of therapeutic alliance, treatment feedback, and clinical outcome among African American women in treatment for co-occurring PTSD and SUD. Journal of Substance Abuse Treatment 2022 (in press).
Published: February 5, 2022
Use of a Digital Therapeutic Tool Increased Abstinence and Retention in Treatment Among Patients with Substance Use Disorders
Meg Brunner, MLIS
Maricich YA, et al. Safety and efficacy of a digital therapeutic for substance use disorder: Secondary analysis of data from a NIDA Clinical Trials Network study. Substance Abuse; 2022;43(1):937-942.
Published: February 5, 2022
Chronic Alcohol Use Impacts Immune System Activation and Inflammation in People Living with HIV
Meg Brunner, MLIS
Underwood ML, et al. Chronic alcohol exposure among people living with HIV is associated with innate immune activation and alterations in monocyte phenotype and plasma cytokine profile. Frontiers in Immunology 2022 (in press). 
Published: January 4, 2022
Increasing Buprenorphine-Naloxone Dose in Response to Recent Opioid Use Appears to Reduce Risk of Relapse
Meg Bruner, MLIS
Rudolph KE, et al. Association between dynamic dose increases of buprenorphine for treatment of opioid use disorder and risk of relapse. Addiction 2022 (in press).
Published: January 4, 2022
Does Buprenorphine-Naloxone Treatment for Opioid Use Disorder Also Help with Chronic Pain?
Meg Brunner, MLIS
Edwards KA, et al. Changes in pain during buprenorphine maintenance treatment among patients with opioid use disorder and chronic pain. Journal of Consulting and Clinical Psychology 2022 (in press). 
Published: September 3, 2022
Treating Clients’ Opioid Use Disorder with Medications Also Reduces Their HIV Viral Load
Meg Brunner, MLIS
Korthuis PT, et al. HIV clinic-based extended-release naltrexone versus treatment as usual for people with HIV and opioid use disorder: A non-blinded, randomized non-inferiority trial. Addiction 2022 (in press).
Published: September 3, 2022
Cannabis Use Risk Reduction Instead of Abstinence as a Meaningful Treatment Outcome
Meg Brunner, MLIS
Sherman BJ, et al. Evaluating cannabis risk reduction as an alternative clinical outcome for cannabis use disorder. Psychology of Addictive Behaviors 2021 (in press). Find it in the CTN Dissemination Library: http://tinyurl.com/ctnlib1497
Published: January 2, 2022
Emergency Department-Initiated Buprenorphine: A Look at ED Procedures Across the Nation
Meg Brunner, MLIS
Guo CZ, et al. Emergency department-initiated buprenorphine protocols: A national evaluation. Journal of the American College of Emergency Physicians Open 2021;2(6):e12606
Published: March 1, 2022
How Does Medication Treatment for Opioid Use Disorder Affect Pain?
Meg Brunner, MLIS
Wang A, et al. Baseline- and treatment-associated pain in the X:BOT comparative effectiveness study of extended-release naltrexone versus buprenorphine-naloxone for OUD. Addiction Biology 2021 (in press). 
Published: March 1, 2022
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