The Prescription Opioid Addiction Treatment Study (POATS), carried out as part of the NIDA Clinical Trials…

• Summary: Emergency departments (EDs) are a key point of access to medical care for patients with opioid use disorder (OUD). This paper describes a quality improvement framework for EDs that could help standardize care, reduce care inequities, and improve outcomes for patients with OUD.…

• People with substance use disorders often exhibit signs of compromised cognitive function, such as issues with attention, reasoning, or spatial processing, compared to the general population.
• Additionally, cognitive impairment is associated with poorer outcomes in treatment,…

• Although cigarette smoking among adults in the United States declined to a rate of 15.5% by 2016, there are vulnerable populations for whom smoking rates remain high. Individuals in substance use disorder (SUD) treatment smoke at rates as high as 84% and die from tobacco-related illnesses…

• When looking at profiles of men and women with opioid use disorder (OUD), a number of gender differences become evident.
• Women report more issues with drug, medical, psychological, family/social, and employment problems, while men report more problems with legal and alcohol-…

• Rising rates of opioid use disorder (OUD) and overdose deaths have become a public health crisis, with deaths from prescription opioid and heroin use increasing four-fold since 1999 and reaching a record high of more than 42,000 in 2016.
• The field of substance use disorder…

• Cannabis use prevalence in the United States more than doubled, from 4.1% to 9.5%, between 2001/2 and 2012-13. In addition, approximately 12% of individuals who have used cannabis in the past year meet criteria for cannabis use disorder.
• However, measures of changes in cannabis…

• The prevalence of cannabis use and cannabis use disorders (CUD) has increased significantly in the last decade, due in part to increasingly legalized access.
• Research has shown that individuals who use cannabis have increased risk of behavioral health conditions, including…

• Opioid use disorder (OUD) treatment outcome is a complex trait that is dependent on both genetic and environmental factors.
• If genetic variants that predicted dropout or relapse from OUD treatment could be identified, patients could be better supported through that treatment with…

• Individuals with substance use disorders (SUDs) are at increased risk for acquisition and transmission of HIV, due in part to specific drug use behaviors, such as injection drug use and needle sharing.
• Substance use disorders are also associated with high-risk sexual behaviors,…