• Pear Therapeutics, producer of a number of digital therapeutic tools, announced this month that the FDA has approved their marketing of a smartphone-based tool call “reSET®” for the treatment of patients with substance use disorder (SUD).
• This is the first time the FDA has cleared…

• Authored by members of the Center for the Clinical Trials Network, in collaboration with the NIDA Intramural Research Program, this article reports on a clinical trial that found that adding clonidine to buprenorphine treatment for opioid dependence increased abstinence and decoupled stress…

• The Centers for Disease Control and Prevention (CDC) recently reported that cigarette smoking among adults in the U.S. has decreased from 20.9% in 2005 to 15.1% in 2015.

As smoking prevalence declines overall, smoking in subgroups becomes increasingly important in terms of…

• Post-traumatic stress disorder (PTSD) and substance use disorders frequently co-occur, and are associated with a host of complex clinical and public health challenges.
• Additionally, the detrimental effects of concurrent substance use disorders (SUD), for example, cocaine and…

• Integration of substance use disorder (SUD) services within primary care provides an opportunity to increase identification of SUD and improve access to treatment for patients.
• However, SUDs are typically under-detected in the primary care setting, and treatment is rarely actually…

• Cannabis use disorder (CUD) is a prevalent and impairing condition, impacting an estimated 1 in 11 adult users of cannabis, and established psychosocial treatments convey limited efficacy.
• In light of recent findings supporting the efficacy of N-acetylcysteine (NAC) for CUD in…

• The use of prescription opioids has increased dramatically in the past 2 decades, with associated increases in opioid misuse/abuse and opioid overdose.
• These are among the most commonly prescribed medications, with 259 million prescriptions written for opioid pain relievers in the…

• Rates of new HIV infections due to sexual transmission in the United States have been increasing in the last several years, comprising 94% of new cases in 2014.
• Additionally, among people who inject drugs, sexual risk behaviors are independently associated with HIV transmission…

• Opioid use disorder (OUD) has been identified as a national public health crisis.
• Numerous studies have shown that OUD is associated with elevated adverse health and social conditions, and elevated mortality has been observed among individuals with OUD treated in addiction…

• Sexual contact is the primary vector for HIV transmission, present in 90.2% of new infections.
• Data suggest that men and women are impacted differently by sexual risk in the context of heterosexual sex, and often this risk includes the combination of substance use and sexual…