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May 1, 2000

African-American Alcoholics: At Greater Risk for Immune Disorders?

  • Alcoholism is known to compromise the immune system
  • African-American alcoholics are at greater risk for certain infectious diseases
  • African-American ethnicity, in conjunction with alcoholism, seems to signify a more compromised immune system
  • These immune…
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June 1, 2000

Some Alcoholics May Self-Medicate With Carbohydrates Between Drinks

  • Alcoholics have reduced levels of serotonin, a brain chemical
  • Alcohol increases serotonin levels, as do carbohydrates
  • Those alcoholics with high cravings for carbohydrates have a unique response to specific diets
  • Carbohydrate craving may be an important clue in…
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June 1, 2000

“Falling Down Drunk” Is Not a Laughing Matter

  • Excessive alcohol consumption clearly has a deleterious effect on brain structure and function
  • Gait and balance, followed by visuospatial abilities, show the greatest alcohol-related deficits
  • Two principal neural systems, the cerebellar-frontal and the corticocortical…
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September 1, 2000

Using Water and Technology to Map Alcohol’s Effects on the Brain

  • Much of the human body, including the brain, is composed of water
  • Sophisticated technology called Diffusion Tensor Imaging (DTI) is sensitive to water in the body
  • Using DTI in a new way, researchers can track water molecules in the brain to examine alcohol’s damaging…
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September 1, 2000

Binge Drinking: A Dangerous Rite of Passage

  • Adolescence is a time when many begin experimenting with alcohol
  • Some adolescents binge drink, that is, drink heavily during a short period of time
  • Adolescent brains may be particularly vulnerable to the neurotoxic effects of alcohol
  • Binge drinking during…
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September 1, 2000

Drinking During Pregnancy: American Indians and African Americans

  • Most health campaigns recommend abstinence from alcohol during pregnancy
  • Some women nonetheless continue to drink at relatively high levels while pregnant
  • This study examines two groups considered most at-risk: American Indians and African Americans
  • …
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September 1, 2000

Measuring Alcohol Levels in Breath, Blood … and Now the Brain

  • The brain is a critical organ system through which alcohol’s effects can lead to intoxication, tolerance and dependence
  • Scientists have found a new means to measure directly alcohol concentrations throughout the brain
  • The technology is called proton (1H)…
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September 1, 2000

Alcohol and the Human Fetal Brain

  • The first step in the metabolism of alcohol is its conversion to acetaldehyde (AcHO)
  • AcHO is a highly reactive and toxic chemical that can damage the cells of all living things
  • In adults, AcHO is blocked from entering the brain
  • The prenatal brain may metabolize…
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October 1, 2000

Fine-Tuning Naltrexone Treatment for Alcoholics

  • In 1994, the Food and Drug Administration approved naltrexone for the treatment of alcoholism
  • It has since proven to be highly effective for many in recovery, but it does not work for everyone
  • A recent study has found that individual metabolism may be a factor in…
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October 1, 2000

Beyond the French Paradox

  • Coronary heart disease (CHD) is the single largest killer of U.S. males and females
  • CHD is caused by partial or complete clogging of the coronary arteries that nourish the heart
  • Atherosclerosis refers to the accumulation of fatty streak lesions in the coronary arteries…
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