Screening, Brief Intervention, and Referral to Treatment (SBIRT) is an evidence-based practice that uses a preventive public health approach to identify and intervene with persons whose pattern of use put them at risk for, or are experiencing, substance-related health and psychosocial problems. SBIRT can also be useful in identifying those with a high likelihood for a substance use disorder. As an effective intervention, SBIRT helps to reduce harmful levels of substance use in health and behavioral health settings.