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NIH Study Reveals Genetic Links to SUDs

March 22, 2023

New NIH study reveals shared genetic markers underlying substance use disordersManhattan plot of the transcriptome-wide association study results for addiction-rf.

Breakthrough findings could lead to more effective prevention and treatment strategies for multiple substance use disorders

By combing through genomic data of over 1 million people, scientists have identified genes commonly inherited across addiction disorders, regardless of the substance being used. This dataset – one of the largest of its kind – may help reveal new treatment targets across multiple substance use disorders, including for people diagnosed with more than one. The findings also reinforce the role of the dopamine system in addiction, by showing that the combination of genes underlying addiction disorders was also associated with regulation of dopamine signaling.


Continue reading NIDA's News Release.


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