This infographic discusses xylazine, a non-opioid animal sedative and tranquilizer, also known as "tranq," that is being used as an additive to the illicit opioid supply, particularly fentanyl.

It covers key concerns including overdose risk, heart and blood pressure problems, necrotic tissue damage, treatment challenges, and harm reduction barriers.

It also contains suggested actions for prevention and treatment professionals.

^{*Originally published April 27, 2023, revised June 5, 2023}